Hello,
no it's not that involved, you just need to add your
SMTP Server - ie. what you would enter into Outlook for your SMTP account - ie. mail.dnncreative.com
Authentication, most people will select either anonymous or basic
Username - this is the username for your email account, ie:
mai@yourdomain.com
Password - is the password for access to that email account
For full info you can view:
How to set up email in DotNetNuke